Is there any relationship between season/weather and oral ulcer in Behçet's disease?

OBJECTIVE Some rheumatic diseases are being influenced by weather conditions. We examined the relationship between oral ulcers and weather/season in Behçet's disease (BD) patients and evaluated the oral ulcers' characteristics by the patients' perspectives. MATERIAL AND METHODS Patients with BD were evaluated using a self-questionnaire, including patients' clinical and demographical characteristics and detailed characteristics of oral ulcers and the association with season. RESULTS The most common site of oral ulcers was the tongue (89%). Of 90 patients, there were predisposing factors in oral ulcers. Among patients with BD, 30 believed that seasonal variation aggravated their oral ulcers, especially in winter and autumn. CONCLUSION The exacerbation of oral ulcers in patients with BD may be related to the seasons. The weather changes in our study are based on the patients' impression; these should be confirmed by objective findings and clinical assessment in further studies.